3.3 – GENE AND CHROMOSOMAL MUTATIONS
COURSE DESCRIPTION
Changes to the DNA sequence or amount of DNA could have huge physiological impact on organisms. This concept illustrates how DNA mutations could result in sickle cell anaemia and Down syndrome in humans.
Learning Outcomes
2(1) explain what is meant by the terms gene mutation and chromosomal aberration. For gene mutation, knowledge of how substitution, addition and deletion could change the amino acid sequence (including frameshift) is required. For chromosomal aberration, knowledge of numerical aberration (including aneuploidy, as in the case of trisomy 21, i.e. Down syndrome) and structural aberration (including translocation, duplication, inversion and deletion) is required
2(m) explain how gene mutations can result in diseases (including sickle cell anaemia)
Use the knowledge gained in this section in new situations or to solve related problems
Lecture Outline
- Mutations
- Gene / Point Mutations
2.1 Effects of Nucleotide Substitutions
2.2 Effects of Nucleotide Insertions or Deletions
- Case studỵ: Gene Mutation resulting in Phenotypic Change
3.1 Sickle-Cell Anaemia
- Causes of Gene Mutation
- Chromosomal Mutation / Aberration
5.1 Change in Chromosome structure
5.2 Change in Chromosome Number
5.2.1 Aneuploidỵ
5.2.2 Polyploidy
Requirements
- Donec porta ultricies urna, faucibus magna dapibus.
- Etiam varius tortor ut ligula facilisis varius in a leo.
- Folutpat tempor tur duis mattis dapibus, felis amet.
- Donec porta ultricies urna, faucibus magna dapibus.
- Etiam varius tortor ut ligula facilisis varius in a leo.
- Folutpat tempor tur duis mattis dapibus, felis amet.
What is the target audience?
- This course is intended for anyone interested in learning to master his or her own body.
- This course is aimed at beginners, so no previous experience with hand balancing skillts is necessary
Aenean viverra tincidunt nibh, in imperdiet nunc. Suspendisse eu ante pretium, consectetur leo at, congue quam. Nullam hendrerit porta ante vitae tristique. Vestibulum ante ipsum primis in faucibus orci luctus et ultrices posuere cubilia Curae; Vestibulum ligula libero, feugiat faucibus mattis eget, pulvinar et ligula.
CURRICULUM
Section 1: Introduction to Handstands
Section 2: Reference Material, Moodboards and Mind Mapping
Wrist Strengthening
While your wrists will certain get stronger from practice and grow accustomed to the stress of the skill, a basic amount of wrist strengthening exercises for several weeks can only help things. I’d recommend working wrist curls and reverse wrist curls for around 6-10 reps for 3 sets. I also strongly recommend trying some sledgehammer levering. Work in 2-3 sets of 3-5 reps. In particular, exercises 1 and 3 are fantastic for building wrist strength and they are much harder than they look! Start with them to get the hang of sledgehammer work before you progress to the other two exercises. I don’t want somebody putting a hole through their floor or their face because they rushed things!Section 3: Sketching out Ideas
- The main objective to the sketching process is to generate super rough thumbnail sketches of what we feel best visually communicates the highlighted words from our mind maps.
- Take as much time as you need for this step — this might be 10 minutes or it might be 10 days.
- Personally, I like to work quickly and try not to analyze or elaborate too much.
- Now, that doesn't mean you should only create a handful of sketches.
- Even though this step only took a couple of hours, I was still able to put over 100 thumbnails on paper.
- The whole point of this process is to flush out the bad ideas and narrow down the good ones until we find that one layout that really speaks to us.
- Also, keep in mind the project brief and have your list in front of you as a reference to avoid getting sidetracked.
- Remember—detail is not needed. Simply flush out the bad ideas and find a great direction.
- Once I feel I have a good direction with the sketches, I'm now ready to take a quick photo with my phone and import it into Illustrator.
Section 4: Conclusions and Evaluation
About Instructors
There are no reviews yet.